ALS-Linked Gene Causes Disease by Changing Genetic Material's Shape at the Mutation Site

Researchers at Johns Hopkins say that they have found one way that a recently discovered genetic mutation might cause two nasty nervous system diseases. While the affected gene may build up toxic RNA and not make enough protein, the researchers report, the root of the problem seems to be snarls of defective genetic material created at the mutation site. The research team, led by Jiou Wang, Ph.D., an assistant professor of biochemistry and molecular ...

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