Targeting glycine receptors in hyperekplexia, startle disease

A drug that can alleviate the exaggerated startle responses seen in hyperekplexia - or "startle disease" - in a mouse model of the condition is discussed in a paper published online in Nature Neuroscience. These findings suggest potential therapeutic avenues for individuals with hyperekplexia.People with hyperekplexia exhibit exaggerated startle responses to unexpected auditory or tactile stimuli, such as hands clapping or taps on shoulder. Previous studies have found that this disease can be caused by mutations in the brain receptor for the neurotransmitter glycine. via Health News from Medical News Today Read More Here..

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