Diagnostic Accuracy of Cerebral Spinal Fluid Biomarkers for Alzheimer Disease

Bottom Line: Cerebral spinal fluid (CSF) levels of (and) #946;-amyloid 42(A (and) #946;42) are linked with the diagnosis of Alzheimer disease (AD) and (A (and) #946;) accumulation in the brain independent of apolipoprotein E (APOE) gene makeup. Authors: Ronald Lautner, M.D., of Sahlgrenska University Hospital, Sweden, and colleagues. Background: With the emergence of biomarker dementia diagnostics, interest in CSF biomarkers associated with AD, including A (and) #946;42 and ...

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