High-dose (HD) bolus IL-2 therapy is one of the most potent forms of immunotherapy for patients with metastatic melanoma and renal cell carcinoma. Approximately 15% of patients respond to HD IL-2 therapy, with almost 5% going into complete remission; however, use of HD IL-2 therapy is limited due to the toxic effects associated with treatment. Because HD IL-2-associated toxicity is severe, it would be beneficial for clinicians to determine if a patient would respond ...Tuesday, 3 December 2013
How to Predict the Outcome for High-Dose IL-2 Therapy in Cancer Patients
High-dose (HD) bolus IL-2 therapy is one of the most potent forms of immunotherapy for patients with metastatic melanoma and renal cell carcinoma. Approximately 15% of patients respond to HD IL-2 therapy, with almost 5% going into complete remission; however, use of HD IL-2 therapy is limited due to the toxic effects associated with treatment. Because HD IL-2-associated toxicity is severe, it would be beneficial for clinicians to determine if a patient would respond ...
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