ZEB1 - transcription factor that is capable of converting non-aggressive basal-type cancer cells into highly malignant, tumor-forming cancer stem cells (CSCs) has been discovered by scientists. Intriguingly, luminal breast cancer cells, which are associated with a much better clinical prognosis, carry this gene in a state in which it seems to be permanently shut down. The researchers, whose findings are published this week in the journal iCell/i, report ...Thursday, 4 July 2013
Gene That Controls Aggressiveness in Breast Cancer Cells Discovered
ZEB1 - transcription factor that is capable of converting non-aggressive basal-type cancer cells into highly malignant, tumor-forming cancer stem cells (CSCs) has been discovered by scientists. Intriguingly, luminal breast cancer cells, which are associated with a much better clinical prognosis, carry this gene in a state in which it seems to be permanently shut down. The researchers, whose findings are published this week in the journal iCell/i, report ...
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