The crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease, has been determined by researchers at the MRC Laboratory of Molecular Biology in the United Kingdom. The results, which are published in iThe EMBO Journal/i, define the position of many of the mutations linked to hereditary Parkinson's disease and explain how these alterations may affect the stability and function of the protein. ...Monday, 3 June 2013
Study Sheds Light on How Disease Mutations Affect the Parkin Protein
The crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease, has been determined by researchers at the MRC Laboratory of Molecular Biology in the United Kingdom. The results, which are published in iThe EMBO Journal/i, define the position of many of the mutations linked to hereditary Parkinson's disease and explain how these alterations may affect the stability and function of the protein. ...
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