Rare, Lethal Childhood Disease - Giant Axonal Neuropathy - Tracked To Failure To Degrade Nerve Cells' Filaments

For the first time, a defective protein that plays a specific role in degrading intermediate filaments (IF), one of three classes of filaments that form the structure of nerve cells, has been discovered by an international team of researchers. The defective protein, gigaxonin, which was first identified in children with a rare and untreatable genetic disease called giant axonal neuropathy (GAN), according to Saleemulla Mahammad, PhD, of the Northwestern Feinberg School of Medicine in Chicago, who presented the data on Dec... via Health News from Medical News Today Read More Here..

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