Undetected DNA Differences Between Unrelated Patients and Donors Responsible for Majority of GVHD Cases

Researchers at Fred Hutchinson Cancer Research Center have found that genetic differences between the DNAs of unrelated patients and donors, which had not been detected previously, are the reason for high rates of acute graft-versus-host disease (GVHD) cases among bone marrow transplant patients who receive tissue matched cells from the donors. The laboratory-based study findings by Effie Petersdorf, M.D., and colleagues soon will be translated to the clinic when ...

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