Intellectual Disability Caused by Too Much Protein HUWE1

2 to 3 % of the children are born with an intellectual disability that could be possibly by a genetic defect, but in 80% of these cases, we do not know - yet - which genes are responsible. VIB researchers at KU Leuven show that increased production of the HUWE1 protein is the cause in some patients. Guy Froyen (VIB/KU Leuven): "The fact that HUWE1 regulates the dose of several other proteins in the brains, has an important impact on the quest for new ...

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