Mouse Model of Noonan Syndrome Created by CNIO Researchers

Noonan syndrome is a rare genetic disease. It presents with a set of pathologies including heart, facial and skeletal alterations, pulmonary stenosis and short stature. The disease is characterized by a greater incidence of haematological problems (mainly juvenile myeloid leukaemia, or childhood leukaemia). There is an estimated incidence of 1 case for every 1,000-2,500 births, and calculations show some 20,000-40,000 people suffer from the disease in Spain. From a genetic ...

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