A team of scientists, led by principal investigator David D. Schlaepfer, PhD, a professor in the Department of Reproductive Medicine at the University of California, San Diego School of Medicine, has found that a protein involved in promoting tumor growth and survival is also activated in surrounding blood vessels, enabling cancer cells to spread into the bloodstream.The findings are published in the online issue of the Journal of Cell Biology.Blood vessels are tightly lined with endothelial cells, which form a permeability barrier to circulating cells and molecules.
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