Researchers Discover How Rho-associated Protein Kinase Modulates Neurite Extension

An essential regulator of cytoskeletal dynamics during the process of neurite extension is rho-associated protein kinase. However, whether Rho kinase regulates microtubule remodeling or the distribution of adhesive proteins to mediate neurite outgrowth remains unclear. By using the ROCK inhibitor, Y-27632, and the agonist, lysophosphatidic acid, Kenen Chen and colleagues from First Affiliated Hospital of Jinan University in China observed that neurite outgrowth, ...

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