Patients With Anaplastic Oligodendroglioma Benefits from Adjuvant PCV

Earlier, results had shown that procarbazine, CCNU and vincristine (PCV) chemotherapy following standard radiation therapy delayed tumor growth and extended the lives of patients with anaplastic oligodendroglial tumors, a hard-to-treat form of brain cancer. A further report on the results of EORTC trial 26951 indicates that CpG island methylator phenotype (CIMP) status and O 6-methylguanine-DNA methyltransferase (MGMT) promoter methylation as assessed by MGMT-STP27 ...

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