Researchers Identify Molecular Switch That Controls Key Cellular Process

A critical molecular switch that regulates autophagy or self eating has been identified by researchers. The researchers identified ASPP2, a tumor suppressor, as a molecular switch that can dictate the ability of a common cancer gene, known as the RAS oncogene, to either stop or promote senescence. As Yihua Wang and researchers in Xin Lu's group at the Ludwig Institute investigated the life cycle of fibroblast cells - the most common connective tissue ...

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